Professor Xiaoliang Sunney Xie is an internationally renowned biophysical chemist, and the Lee Shao-kee professor of Peking University. After a career at Pacific Northwest National Laboratory, he became the first tenured professor at Harvard University among Chinese scholars who went to the US since the Reform in China. As a pioneer of single-molecule biophysical chemistry, coherent Raman scattering microscopy, and single-cell genomics, he made major contributions to the emergence of these fields. In particular, his inventions in single-cell genomics have been used in in vitro fertilization to benefit hundreds of couples in China by avoiding the transmission of monogenic diseases to their newborns.
Proposed Title: “Label-Free Optical Imaging with the Contrast of Molecular Vibration: Seeing the Invisibles for Biology and Medicine“
Stimulated Raman scattering (SRS) microscopy is a label-free and noninvasive imaging technique using vibration spectroscopy as the contrast mechanism. Highly sensitive, SRS has opened a wide range of biomedical applications, allowing for imaging small molecules, such as metabolites, drug molecules, or neurotransmitters.